Hydrogen Sulfide Releasing Agents Abstract Hydrogen sulfide (H2S) has demonstrated several essential critical care benefits when delivered properly in low doses. The current state of the art delivery systems rely on gaseous delivery of H2S to patients. WSU researchers have developed chemical agents that controllably decompose to release H2S and demonstrated their efficacy in biological tissues. Applications and Advantages § Timed-release § Biocompatible IP Status US patent application pending and PCT/US2011/062820 published as WO2012/05242 Publications Zhao, Y.; Wang, H.; Xian, M.; Cysteine activated hydrogen sulfide (H2S) donors. J. Am. Chem. Soc., 2011, 133, 15. Zhao, Y.; Bhushan, S.; Yang, C.; Otsuka, H.; Stein, J.D.; Pacheco, A.; Peng, B.; Devarie, N.O.; Aguilar, HC; Lefer, D.J.; Xian, M.; Controllable hydrogen sulfide donors and the activity against myocardial ischemia-reperfusion injury. ACS Chem. Biol. 2013, in press. See trade magazine article at: http://cen.acs.org/articles/91/web/2013/04/Hydrogen-Sulfide-Donors-Protect-Heart.html Learn More Punam Dalai Technology Licensing Associate Washington State University (509) 335-1216 punam.dalai@wsu.edu Reference No: 1086-OC Bookmark this page Download as PDF Inventors Ming Xian Hua Wang Yu Zhao Key Words Chemistry