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Hydrogen Sulfide Releasing Agents
Abstract
Hydrogen sulfide (H2S) has demonstrated several essential critical care benefits when delivered properly in low doses. The current state of the art delivery systems rely on gaseous delivery of H2S to patients. WSU researchers have developed chemical agents that controllably decompose to release H2S and demonstrated their efficacy in biological...
Published: 5/25/2023
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Inventor(s): Ming Xian, Hua Wang, Yu Zhao
Keywords(s): Chemistry
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Acidic organophosphorus separation of americium and curium
Unmet Need: Acidic separation of americium from curium for closing fuel cycleThe separation of americium from curium has been a challenging step for completely closing the nuclear fuel cycle. Both elements are most stable in the trivalent oxidation state in acidic solution. Compounding this issue is their nearly identical ionic radii. The identical...
Published: 5/25/2023
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Inventor(s): Joseph Lapka, Ken Nash, Matthew Risenhuber, Jenifer Shafer
Keywords(s): Chemistry, Nuclear Energy, Solvent Extraction
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Hydrogen Sulfide Detection
Abstract
Hydrogen sulfide (H2S) has been known as a toxic pollutant for years. However, H2S, has been recently recognized as an important signaling molecule of the cardiovascular system, the inflammatory system and the nervous system. H2S is now known as the third endogenous gaseotransmitter, alongside nitric oxide (NO) and carbon monoxide. There...
Published: 5/25/2023
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Inventor(s): Ming Xian, Chunrong Liu
Keywords(s): Chemistry
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Biobased Epoxy Resins and Curing Agents using Rosin Acids as Building Blocks
Abstract WSU inventors have developed epoxy resin systems and carboxylic terminated polyesters using rosin acids as building blocks. This provides a method to make epoxy resin systems that do not contain Bisphenol A (BPA). Current powder coating polyester resins are built largely on tere-or isophthalic acid and trimellitic anhydride as rigid monomers...
Published: 4/28/2023
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Inventor(s): Jinwen Zhang, Ming Xian, Xiaoqing Liu
Keywords(s): Advanced Materials, Chemistry, Clean Tech
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Synthesis of Mesoporous Calcium Silicate for Controlled Release of Protein or Drug
Abstract This WSU invention relates to mesoporous calcium silicate compositions and methods for producing mesoporous calcium silicate for controlled release of bioactive agents. Bioactive agents can include protein growth factors, pharmaceutical drugs, antibiotics, antimicrobial agents, and polypeptides just to name a few potential agents. With this...
Published: 4/28/2023
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Inventor(s): Susmita Bose, Amit Bandyopadhyay, Weichang Xue
Keywords(s): Chemistry, Global Human and Animal Health, Pharmaceutical
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Chemical Ligation
Researchers at Washington State University Department of Chemistry have invented an improved method of native chemical ligation. The method involves the ligation of a peptide thioacid with an aziridinyl peptide to yield an aziridinyl peptide ligation product without the use ofprotecting groups. Ring opening of the ligation product ultimately yields...
Published: 4/28/2023
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Inventor(s): Philip Garner
Keywords(s): Chemistry
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