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Hydrogen Sulfide Releasing Agents
Abstract
Hydrogen sulfide (H2S) has demonstrated several essential critical care benefits when delivered properly in low doses. The current state of the art delivery systems rely on gaseous delivery of H2S to patients. WSU researchers have developed chemical agents that controllably decompose to release H2S and demonstrated their efficacy in biological...
Published: 5/25/2023
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Inventor(s): Ming Xian, Hua Wang, Yu Zhao
Keywords(s): Chemistry
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Sulfur dioxide releasing agents
Abstract Sulfur dioxide has long been considered a toxic environmental pollutant and byproduct of industrial processing. But, more recently it has become evident that sulfur dioxide may also have a regulatory role in mammalian pulmonary systems. Researchers at WSU have discovered novel pharmaceutically relevant compounds that take advantage of this...
Published: 5/25/2023
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Inventor(s): Zhenhua Yang, Jacob Day, Chuan Dong, Ming Xian
Keywords(s):
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Fluorescent probes for the detection of hydrogen polysulfides
AbstractEndogenous hydrogen polysulfides have recently been recognized as important regulators in sulfur-related redox biology. H2Sn can activate tumor suppressors, ion channels, and transcription factors with higher potency than H2Sn. But, a major hurdle in this field is the lack of reliable and convenient methods of H2Sn detection. Researchers at...
Published: 8/25/2023
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Inventor(s): Ming Xian, Wei Chen
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Hydrogen Sulfide Detection
Abstract
Hydrogen sulfide (H2S) has been known as a toxic pollutant for years. However, H2S, has been recently recognized as an important signaling molecule of the cardiovascular system, the inflammatory system and the nervous system. H2S is now known as the third endogenous gaseotransmitter, alongside nitric oxide (NO) and carbon monoxide. There...
Published: 5/25/2023
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Inventor(s): Ming Xian, Chunrong Liu
Keywords(s): Chemistry
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Biobased Epoxy Resins and Curing Agents using Rosin Acids as Building Blocks
Abstract WSU inventors have developed epoxy resin systems and carboxylic terminated polyesters using rosin acids as building blocks. This provides a method to make epoxy resin systems that do not contain Bisphenol A (BPA). Current powder coating polyester resins are built largely on tere-or isophthalic acid and trimellitic anhydride as rigid monomers...
Published: 4/28/2023
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Inventor(s): Jinwen Zhang, Ming Xian, Xiaoqing Liu
Keywords(s): Advanced Materials, Chemistry, Clean Tech
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pH-Controlled Hydrogen Sulfide Donors
Unmet Need: Current Market Lack controllable H2S donorRecent studies suggest that the production of endogenous H2S and the exogenous administration of H2S can exert protective effects in many pathologies. For example, H2S has been shown to relax vascular smooth muscle, induce vasodilation of isolated blood vessels, and reduce blood pressure. H2S can...
Published: 5/25/2023
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Inventor(s): Ming Xian, Jianming Kang, David Lefer
Keywords(s):
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