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Gas Phase Mobility Selection of Ions Prior to Mass Spectrometric Analysis
Abstract Traditionally, ion mobility spectrometry (IMS) has been used for the analysis of gas phase compounds, however, with the advent of electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI) the technique's scope of analysis has greatly expanded. The powerful prospects of combining IMS and ion mobility mass spectrometry...
Published: 5/25/2023
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Inventor(s): Brian Clowers, Herbert Hill
Keywords(s): Instrumentation/Equipment
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Breathalyzer for Psychoactive drugs
Unmet Need: Lack of reliable on site detection method for psychoactive drugs
Rapid detection of drugs of abuse in the field requires innovative approaches for collection and detection. Current approaches such as collection of blood, saliva, urine, sweat, or other bodily fluids may seem attractive but also have the potential to collect identifying...
Published: 1/5/2024
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Inventor(s): Herbert Hill, Brian Clowers
Keywords(s):
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Liquid Phase Ion Mobility Spectrometry (LPIMS)
Abstract The present choice of analytical separation methods that occur under ambient pressure conditions are generally limited to gas chromatography(GC), liquid chromatography (HPLC), capillary zone electrophoresis (CZE) and ion mobility spectrometry (IMS). IMS is about 3 times more efficient than HPLC, 130 times more efficient than GC and almost as...
Published: 5/25/2023
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Inventor(s): Herbert Hill, Maggie Tam
Keywords(s): Instrumentation/Equipment
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Voltage Sweep Ion Mobility Spectrometry
AbstractIon mobility spectrometry (IMS), is a powerful tool commonly used for security applications (e.g. search for explosives, narcotics, and other trace contrabands) but it doesn’t achieve optimal separation power with both small and large ions simultaneously. Similar to the general elution problem of chromatographic experiments, small ions...
Published: 5/25/2023
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Inventor(s): Herbert Hill, Eric Davis, William Siems, Michael Williams
Keywords(s): Instrumentation/Equipment
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A New Gas-Phase Atmospheric Pressure Ion Detection Mechanism
AbstractResearchers at WSU have produced a novel Radiative Ion-Ion Recombination: A New Gas-Phase Atmospheric Pressure Ion Detection Mechanism.All the present atmospheric ion detectors including flame ionization detectors and ion mobility spectrometers utilize Fraday plate designs for ion detection. These plates collect charge and convert it to amplified...
Published: 4/28/2023
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Inventor(s): Eric Davis, William Siems, Herbert Hill
Keywords(s): Instrumentation/Equipment
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