Search Results - sperm

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Targeting ARRDC5 for Male Contraception
Unmet Need: ARRDC5, an essential regulator of mammalian spermatogenesis Identification of a molecule arrestin-domain containing ARRDC5 as an essential regulator of mammalian spermatogenesis, which could potentially be targeted for the development of male contraceptives. By studying mice lacking the ARRDC5 gene, inventors observed that mice were infertile...
Published: 4/25/2024   |   Inventor(s): Jon Oatley, Mariana Ianello Giassetti
Keywords(s): Biotechnology, Contraception, Sperm
Germline Ablation in Goats
Unmet Need: Accurate and dependable breeding of desired traits While livestock all over the world exhibit a variety of traits that allow them to survive in different environments, they don’t always have other qualities breeders deem to be desirable, like high quality meat or growth potential. In the past, people would bring in a male –...
Published: 5/25/2023   |   Inventor(s): Jon Oatley, Irina Polejaeva
Keywords(s): Agriculture, Animal Research, Genome editing, Germline Ablation, Nanos2, Sperm, Spermatgonial stem cell