Office of Commercialization Search Results - biotechnology

Search Results - biotechnology

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Real-time PCR primers for native yeasts of grape
Monitoring Native Yeast Populations in VineyardsUnmet Need: Effective strategy to identify and quantify native Yeast populationsNative yeasts are part of the microbial community in grape vineyards and play roles in alcoholic fermentation and wine quality. Monitoring their populations during fermentation and after bottling is important as it will provide...
Published: 9/16/2019   |   Inventor(s): Xuefei Wang, Patricia Okubara
Keywords(s): Agriculture and Plant Sciences, Biotechnology, Diagnostics, Technology
Whole transcriptome start site sequencing (WTSS-seq) method
Unmet Need: Effective methods for genetic profilingRNA contributes significantly to the complexity of information transfer from genome to phenome. Alternative transcripts have been considered as biomarkers for improved early diagnosis of diseases, and as targets for designing novel treatment options. Recent studies have revealed that the transcriptome...
Published: 8/13/2019   |   Inventor(s): Zhihua Jiang, Jennifer Michal, Xiang Zhou
Keywords(s): Biotechnology, Diagnostics, High throughput, Tool
Fungus for control of Varroa mites in Honeybees
Unmet Need: Effective controlling agents for Varroa mitesVarroa mites are a devastating parasite considered the top driver of honey bee colony losses over the past several decades. Products for varroa control are desperately needed. The general idea of using entomopathogenic fungi to control Varroa mites had been explored previously. However, none...
Published: 6/17/2019   |   Inventor(s): Nicholas Naeger, Jennifer Han, Walter Sheppard, Lori Carris
Keywords(s): Agriculture, Biotechnology
Anti-inflammatory activity by Doxorubicin-Conjugated Nanoparticles
Unmet Need: Effective therapy for inflammatory disorders. Inflammation is a key physiological response to bacterial and viral infections. Neutrophils are an important part of the innate immune response and normally maintain a constant population by undergoing spontaneous apoptosis after a short lifespan of 8-20 hours. However, it is well known that...
Published: 6/7/2019   |   Inventor(s): Zhenjia Wang, Canyang Zhang
Keywords(s): Biotechnology
Production of Complex Flavonoids
Unmet Need: Production of lipophilic methoxylated flavonoids Numerous methoxylated flavonoids exhibit pronounced bioactivities. Their biotechnological production and diversification are therefore of interest to pharmaceutical and nutraceutical industries. Efforts to engineer flavonoid mechanisms have been conducted earlier but there has not been much...
Published: 8/14/2018   |   Inventor(s): David Gang, Anna Berim
Keywords(s): Biotechnology, Engineering, Natural products
Calcium/Calmodulin-Regulated Plant Immunity
Unmet Need: Understanding the mechanism of regulation of salicylic acid by Ca2+ signaling Intracellular calcium transients during plant-pathogen interactions are necessary early events leading to local and systemic acquired resistance. Salicylic acid, a critical messenger, is also required for both these responses, but whether and how salicylic acid...
Published: 2/22/2018   |   Inventor(s): B Poovaiah, A Reddy, Gul Ali, Tianbao Yang, Kayla Simons, Jingguo Hou, Liqun Du
Keywords(s): Agriculture and Plant Sciences, Biotechnology