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Mice with humanized telomere homeostasis
Unmet Need: The imperative need for mouse models in advancing research on human aging and tumorigenesis
Telomeres play a key role in human aging and tumorigenesis. However, studying telomeres in mouse models presents challenges due to significant difference in telomere length, which is up to 10 times longer than in humans. To address this limitation,...
Published: 1/9/2024
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Inventor(s): Jiyue Zhu, Shuwen Wang, Fan Zhang, De Cheng
Keywords(s): Animal Research, Biotechnology, Cancer and aging, Genome editing, Human Research, Male Infertility, Telomere and telomerase
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Germline Ablation in Goats
Unmet Need: Accurate and dependable breeding of desired traits
While livestock all over the world exhibit a variety of traits that allow them to survive in different environments, they don’t always have other qualities breeders deem to be desirable, like high quality meat or growth potential. In the past, people would bring in a male –...
Published: 5/25/2023
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Inventor(s): Jon Oatley, Irina Polejaeva
Keywords(s): Agriculture, Animal Research, Genome editing, Germline Ablation, Nanos2, Sperm, Spermatgonial stem cell
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Methods and Compositions for Prevention and Treatment of Apicomplexan Infections
Unmet Need: Effective treatment options to combat Apicomplexan parasitic infectionsDiseases caused by apicomplexan parasites, such as cryptosporidiosis and malaria are among the most devastating to humans and their domestic animals. Ongoing discovery and development of new drugs to treat these diseases is a medical and veterinary imperative. For example,...
Published: 5/25/2023
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Inventor(s): Roberta O'Connor, Eric Schmidt
Keywords(s): Animal Research, anti-parasitic drugs, Global Human and Animal Health, Natural products, Pharmaceutical, Therapeutics, Veterinary
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